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The plasminogen activator and esterase activities of the two forms of urokinase

โœ Scribed by E.B. Ong; M.E. Soberano; A.J. Johnson; E.D. Dharmgrongartama

Book ID
119034569
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
632 KB
Volume
24
Category
Article
ISSN
0049-3848

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The generation of the broad specificity serine protease plasmin in the pericellular environment is regulated by binding of the urokinase-type plasminogen activator (uPA) to its specific glycosylphosphatidylinositol (GPI)-anchored cell-surface receptor, uPAR. This interaction potentiates the reciproc