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Differences in the activation rates of plasminogen by tissue plasminogen activator and urokinase

โœ Scribed by Akikazu Takada; Kengo Shizume; Masaru Cho; Yumiko Takada


Book ID
119036813
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
723 KB
Volume
45
Category
Article
ISSN
0049-3848

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Urokinase plasminogen activator (uPA) is a serine protease involved in cancer invasion and metastasis. uPA mediates its action while attached to a membrane-bound receptor (uPAR). In this investigation we show that uPAR levels correlate with uPA levels in human breast cancers. uPAR levels, however, d