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The Pivotal Role of Phosphoinositide-3 Kinase in the Human Somatostatin sst4 Receptor-Mediated Stimulation of p44/p42 Mitogen-Activated Protein Kinase and Extracellular Acidification

✍ Scribed by Keiran S.M. Smalley; Wasyl Feniuk; Lynda A. Sellers; Patrick P.A. Humphrey


Book ID
115584450
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
152 KB
Volume
263
Category
Article
ISSN
0006-291X

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## Abstract Results presented in this study indicate that in human embryonic kidney 293 cells (HEK 293), the ghrelin receptor growth hormone secretagogue receptor type 1a (GHS‐R1a) activates the extracellular signal‐related kinases 1 and 2 (ERK 1/2) via three pathways. One pathway is mediated by th