✦ LIBER ✦

THE physiology of jaundice: Molecular and functional characterization of the Crigler-Najjar syndromes

✍ Scribed by Carl L. Berg

Publisher: John Wiley and Sons
Year: 1995
Tongue: English
Weight: 439 KB
Volume: 22
Category: Article
ISSN: 0270-9139
DOI: 10.1002/hep.1840220448

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

The presence of a microsomal UDP-glucuro

The presence of a microsomal UDP-glucuronyl transferase for bilirubin in homozygous jaundiced gunn rats and in the crigler-najjar syndrome

✍ Gerard B. Odell; Julio O. Cukier; Glenn R. Gourley 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 English ⚖ 962 KB

The infusion of a closely related derivative of bilirubin, its dimethyl diester (DME), into jaundiced (jj) Gunn rats was associated with biliary excretion of mono-and diglucuronides of bilirubin. In uitro incubation of DME with liver microsomes from jj rats demonstrated sequential demethylation and

Crigler-Najjar syndrome in The Netherlan

Crigler-Najjar syndrome in The Netherlands: Identification of four novel UGT1A1 alleles, genotype–phenotype correlation, and functional analysis of 10 missense mutants

✍ Nina Sneitz; Conny T. Bakker; Robert J. de Knegt; Dicky J.J. Halley; Moshe Finel 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 192 KB

Crigler-Najjar syndrome (CN), caused by deficiency of UGT isoform 1A1 (UGT1A1), is characterized by severe unconjugated hyperbilirubinemia. In this study we have analyzed 19 CN patients diagnosed in The Netherlands (18) and in Belgium (1), and have identified 14 different UGT1A1 mutations, four of w

Sequence of exons and the flanking regio

Sequence of exons and the flanking regions of human bilirubin-UDP-glucuronosyltransferase gene complex and identification of a genetic mutation in a patient with Crigler-Najjar syndrome, type I

✍ Piter J. Bosma; Namita Roy Chowdhury; Bart G. Goldhoorn; Martin H. Hofker; Ronal 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 814 KB

Crigler-Najjar syndrome, type I is a heterogeneous

Physiological and Molecular Biological C

Physiological and Molecular Biological Characterization of Ammonia Oxidation of the Heterotrophic NitrifierPseudomonas putida

✍ Michael Daum; Wolfgang Zimmer; Hans Papen; Karin Kloos; Kerstin Nawrath; Hermann 📂 Article 📅 1998 🏛 Springer 🌐 English ⚖ 623 KB

Characterization of the acquired immune

Characterization of the acquired immune deficiency syndrome at the cellular and molecular level

✍ Douglas J. Barrett 📂 Article 📅 1984 🏛 Springer 🌐 English ⚖ 737 KB

The acquired immunodeficiency syndrome (AIDS) is a new disease characterized by severe dysfunction of both the T cell and B cell systems, occurring in previously healthy individuals. Affected individuals may have recurrent and chronic opportunistic infections and/or Kaposi's sarcoma or other maligna

The clinical and molecular spectrum of a

The clinical and molecular spectrum of androgen insensitivity syndromes

✍ Hiort, Olaf; Sinnecker, Gernot H. G.; Holterhus, Paul-Martin; Nitsche, Esther M. 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 28 KB 👁 2 views

Androgen insensitivity syndromes (AIS) are due to end-organ resistance to androgenic steroids in males leading to defective virilization of the external genitalia. The phenotype encompasses a wide array of genital ambiguity and may range from completely female to undervirilized but unequivocally mal