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The physiological response of thrombopoietin (c-Mpl ligand) to thrombocytopenia in the rat

โœ Scribed by Chun Yang; Yan Chun Li; David J. Kuter

Book ID
108672252
Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
232 KB
Volume
105
Category
Article
ISSN
0007-1048

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BACKGROUND. Chronic myelogenous leukemia (CML) represents a paradigm of the stepwise increment in disease aggressiveness, resistance to therapy, and transformation. Thrombopoietin (TPO) and its receptor, c-mpl, support the proliferation of multiple types of immature hematopoietic progenitor cells, a