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Thrombopoietin Agonists for the Treatment of Thrombocytopenia in Liver Disease and Hepatitis C

✍ Scribed by Dusheiko, Geoffrey


Book ID
122337921
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
291 KB
Volume
13
Category
Article
ISSN
1089-3261

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Thrombocytopenia is common in advanced-stage liver disease and is partly caused by inadequate thrombopoietin (TPO) production in the failing liver. Treatment of chronic hepatitis C with interferon alfa (IFN-␣) often induces thrombocytopenia, sometimes even leading to discontinuation of treatment. TP