The photochemistry of taxol: Synthesis of a novel pentacyclic taxol isomer
β Scribed by Shu-Hui Chen; Charles M. Combs; Susan E. Hill; Vittorio Farina; Terrence W. Doyle
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- French
- Weight
- 114 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0040-4039
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us compare the C-C bonds in butadiene (8, Frame 21), and acrolein (9, Frame 22). The illustrations present ELF values in a plane lying 1 Bohr above the plane of the nuclei and intersecting the x-bonding region, and show that the x component of the C-C bond is larger in 9 than it is in 8. H, 3 H, ,H
Absfhzct. The optically active tax01 A-ring unit 3 was synthesized in 11 steps from 2-isopropyl-2-propenol. The stereogenic centers were introduced via the asymmeuic glyoxylateene reaction and the Sharpless asymmetric epoxidation reaction. The total synthesis of tax01 (1) and analogous compounds ha