The photochemical conversion of some heterocyclic acraldehydes into derivatives of the corresponding propionic acids
β Scribed by L.S. Davies; Gurnos Jones
- Book ID
- 108385068
- Publisher
- Elsevier Science
- Year
- 1970
- Tongue
- French
- Weight
- 150 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
## Abstract magnified image A simple one pot synthetic method for the isomerization of cephem double bond from the natural 3βposition to 2βcephem positions is affected by silylation. Thus cephalosporin acids are treated with Ntrimethylsilylacetamide (MSA) or __N,O__βbis(trimethylsilyl)acetamide (B
Heterocyclic aldehydes such as 2-thiophenecarbaldehyde (1) condense with 3-aroylpropionic acids 2 or their sodium salts to give the enol lactones 3a-d of 3-aroyl-2-(2-thienylmethy-1ene)propionic acids. Isomerization of 3 ad leads to the corresponding 4-arylbenzo[b]thiophene-6-carboxylic acids 4a-d.