The pharmacology of the behavioral and hypothermic responses of rats to 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT)
β Scribed by G. M. Goodwin; R. J. Souza; A. R. Green; D. J. Heal
- Publisher
- Springer
- Year
- 1987
- Tongue
- English
- Weight
- 671 KB
- Volume
- 91
- Category
- Article
- ISSN
- 0033-3158
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The effects of the putative serotonin agonist 8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT) on food intake in non-deprived male rats were investigated. Low doses of 8-OH-DPAT (15-60 lag/kg) significantly increased food intake, without affecting drinking, grooming, rearing or locomotion. Micros
Recent studies have suggested that anxiety may be an important factor in the non-opioid analgesic response to defeat in muroid rodents. In the present study, we have examined the influence of the 5-HT~A receptor agonist, 8-OH-DPAT, on basal nociception and defeat analgesia in male DBA/2 mice. Our re