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The pharmacology of sulpiride—A dopamine receptor antagonist

✍ Scribed by O'Connor, S.E.; Brown, R.A.

Book ID
120450074
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
981 KB
Volume
13
Category
Article
ISSN
0306-3623

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PCILO and CD. Conformational study of su
PCILO and CD. Conformational study of sulpiride, a dopamine antagonist
✍ Han van de Waterbeemd; Bernard Testa 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 German ⚖ 285 KB 👁 1 views

## Abstract The conformational behaviour of sulpiride has been investigated by the quantum mechanical PCILO method and by CD. measurements. The results indicate the predominance of a folded, intramolecularly H‐bonded conformer, with extended conformers being only slightly less stable. The pharmacol