𝔖 Bobbio Scriptorium
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THE PHARMACOLOGICAL ROLE OF P-GLYCOPROTEIN IN THE INTESTINAL EPITHELIUM

✍ Scribed by JUDITH VAN ASPEREN; OLAF H. VAN TELLINGEN; JOS H. BEIJNEN


Book ID
118770529
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
93 KB
Volume
37
Category
Article
ISSN
1043-6618

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Background: Altered P-glycoprotein expression (P-gp/MDR1) and/or function may contribute to the pathogenesis of gastrointestinal inflammatory disorders. Low intestinal mRNA levels of the pregnane X receptor (PXR) have been linked to low MDR1 mRNA levels in patients with ulcerative colitis (UC). Here