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Expression of P-Glycoprotein in the Intestinal Epithelium of Dogs with Lymphoplasmacytic Enteritis

โœ Scribed by S. Van der Heyden; G. Vercauteren; S. Daminet; D. Paepe; K. Chiers; I. Polis; T. Waelbers; M. Hesta; S. Schauvliege; B. Wegge; R. Ducatelle


Book ID
113696090
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
876 KB
Volume
145
Category
Article
ISSN
0021-9975

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Decreased P-glycoprotein (P-gp/MDR1) exp
โœ Hans Blokzijl; Sara Vander Borght; Lisette I.H. Bok; Louis Libbrecht; Mariska Ge ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 937 KB

Background: Altered P-glycoprotein expression (P-gp/MDR1) and/or function may contribute to the pathogenesis of gastrointestinal inflammatory disorders. Low intestinal mRNA levels of the pregnane X receptor (PXR) have been linked to low MDR1 mRNA levels in patients with ulcerative colitis (UC). Here