The pharmacological impact of ATP-binding cassette drug transporters on vemurafenib-based therapy
β Scribed by Wu, Chung-Pu; V. Ambudkar, Suresh
- Book ID
- 122637872
- Publisher
- Elsevier
- Year
- 2014
- Tongue
- English
- Weight
- 803 KB
- Volume
- 4
- Category
- Article
- ISSN
- 2211-3835
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Active drug efflux transporters of the ATP binding cassette (ABC)-containing family of proteins have a major impact on the pharmacological behavior of most of the drugs in use today. Pharmacological properties affected by ABC transporters include the oral bioavailability, hepatobiliary, direct intes
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