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The pharmacokinetics of oral and intravenous prenalterol in young, healthy volunteers

✍ Scribed by A. F. Clarke; D. B. Jack; M. J. Kendall; S. R. Smith

Publisher: John Wiley and Sons
Year: 1986
Tongue: English
Weight: 276 KB
Volume: 7
Category: Article
ISSN: 0142-2782
DOI: 10.1002/bdd.2510070107

No coin nor oath required. For personal study only.

✦ Synopsis

The pharmacokinetics of prenalterol in healthy young volunteers after i.v. and oral dosing has been studied. There is evidence of non-linearity following the i.v. dosing. Evidence of dose-dependent pharmacokinetics following i.v. dosing has been obtained. The sustained-release formulation is very effective: almost 12 h were needed to achieve 50 per cent of the total AUC.

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