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The pharmacokinetics of diethanolamine in Sprague–Dawley rats following intravenous administration

✍ Scribed by A.L Mendrala; J.M Waechter Jr.; G.A Bormett; M.J Bartels; W.T Stott


Book ID
117449842
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
141 KB
Volume
39
Category
Article
ISSN
0278-6915

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All-trans-retinoyl-b-D-glucuronide (RAG) is an endogenous active metabolite of all-trans-retinoic acid (ATRA). In the present study, the pharmacokinetics of RAG was examined after the administration of a single intravenous does (5, 10, or 15 mmol/kg) and of multiple daily intravenous doses (5 mmol/k