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The pharmacokinetics of (+)- and (−)-primaquine in the isolated perfused rat liver preparation

✍ Scribed by Stephen A. Ward; George W. Mihaly; Deborah D. Nicholl; Alasdair M. Breckenridge; Geoffrey Edwards


Book ID
115779536
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
253 KB
Volume
36
Category
Article
ISSN
0006-2952

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Primaquine disposition in the isolated p
✍ Michael D. Coleman; Lawrence Fleckenstein; Melvin H. Heiffer 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 524 KB

The disposition of primaquine (0.75 mg, 5 pC1) has been investigated in the isolated perfused rat liver (IPRL) preparation alone and concurrently with mefloquine. In both groups, primaquine concentrations declined exponentially. There were no significant differences between the respective groups in