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The disposition of primaquine in the isolated perfused rat liver: Stereoselective formation of the carboxylic acid metabolite

โœ Scribed by Deborah D. Nicholl; Geoffrey Edwards; Stephen A. Ward; Michael L'E. Orme; Alasdair M. Breckenridge


Book ID
115779675
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
558 KB
Volume
36
Category
Article
ISSN
0006-2952

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Primaquine disposition in the isolated p
โœ Michael D. Coleman; Lawrence Fleckenstein; Melvin H. Heiffer ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 524 KB

The disposition of primaquine (0.75 mg, 5 pC1) has been investigated in the isolated perfused rat liver (IPRL) preparation alone and concurrently with mefloquine. In both groups, primaquine concentrations declined exponentially. There were no significant differences between the respective groups in