## Abstract In glucose exchange transport into red blood cells the rate of glucose uptake showed two pH dependent maxima, with the larger at approximately pH 7.5 and the smaller one at pH 3. In the studied pH range the relation between the rate of glucose uptake and the substrate concentration fol
The pH-dependence of glucose transport inhibition by local anesthetics in human erythrocytes
β Scribed by L. Lacko; B. Wittke; I. Lacko
- Book ID
- 112652501
- Publisher
- Springer
- Year
- 1978
- Tongue
- English
- Weight
- 301 KB
- Volume
- 34
- Category
- Article
- ISSN
- 1420-682X
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π SIMILAR VOLUMES
## Abstract Local anesthetics inhibit the exchange transport of glucose in human erythrocytes. All compounds tested showed a competitive inhibition except lidocaine and baycaine causing a nonβcompetitive one. Moreover the transport system can bind two inhibitor molecules to one transport site as de
## Abstract The inhibition of glucose transport by the nonβionizable localβanesthetic benzylalcohol is of the mixed type and independent of pH. The affinity of benzylalcohol to the free carrier is about three times larger than that to the carrierβglucose complex.