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The pH-dependence of glucose transport inhibition by local anesthetics in human erythrocytes

✍ Scribed by L. Lacko; B. Wittke; I. Lacko


Book ID
112652501
Publisher
Springer
Year
1978
Tongue
English
Weight
301 KB
Volume
34
Category
Article
ISSN
1420-682X

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✍ L. Lacko; B. Wittke; P. Geck πŸ“‚ Article πŸ“… 1972 πŸ› John Wiley and Sons 🌐 English βš– 370 KB πŸ‘ 1 views

## Abstract In glucose exchange transport into red blood cells the rate of glucose uptake showed two pH dependent maxima, with the larger at approximately pH 7.5 and the smaller one at pH 3. In the studied pH range the relation between the rate of glucose uptake and the substrate concentration fol

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## Abstract The inhibition of glucose transport by the non‐ionizable local‐anesthetic benzylalcohol is of the mixed type and independent of pH. The affinity of benzylalcohol to the free carrier is about three times larger than that to the carrier‐glucose complex.