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Interaction of local anesthetics with the transport system of glucose in human erythrocytes

✍ Scribed by L. Lacko; B. Wittke; I. Lacko

Publisher: John Wiley and Sons
Year: 1977
Tongue: English
Weight: 452 KB
Volume: 92
Category: Article
ISSN: 0021-9541
DOI: 10.1002/jcp.1040920214

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✦ Synopsis

Abstract

Local anesthetics inhibit the exchange transport of glucose in human erythrocytes. All compounds tested showed a competitive inhibition except lidocaine and baycaine causing a non‐competitive one. Moreover the transport system can bind two inhibitor molecules to one transport site as described for tetracaine and oxybuprocaine.

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