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The Petasis Reaction: Microscale Synthesis of a Tertiary Amine Antifungal Analog

✍ Scribed by Koroluk, Katherine J.; Jackson, Derek A.; Dicks, Andrew P.


Book ID
120261566
Publisher
American Chemical Society
Year
2012
Tongue
English
Weight
249 KB
Volume
89
Category
Article
ISSN
0021-9584

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A practical synthesis of peptide mimetic
✍ Sean R Klopfenstein; Jack J Chen; Adam Golebiowski; Min Li; Sean X Peng; Xia Sha πŸ“‚ Article πŸ“… 2000 πŸ› Elsevier Science 🌐 French βš– 152 KB

The boronic acid Mannich reaction (Petasis reaction) is demonstrated on a solid support. Peptide mimetics are formed from N-alkylated amino acid resin esters, glyoxylic acid and boronic acids.