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The peroxisome proliferator-activated receptor γ2 gene Pro12Ala polymorphism and serum C-reactive protein in general Japanese population

✍ Scribed by Kazuhiko Kotani; Naoki Sakane; Yoshiko Sano; Kyoko Saiga; Masahiko Tabata; Youichi Kurozawa


Book ID
116347637
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
121 KB
Volume
383
Category
Article
ISSN
0009-8981

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Background Peroxisome proliferators-activated receptor γ (PPAR γ ) is a nuclear hormone receptor that serves as a master regulator of adipocytesspecific genes contributing to adipocytes differentiation, susceptibility to obesity, and insulin sensitivity. The substitution of proline to alanine at cod