Studies of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-γ2 (PPAR-γ2) gene in relation to insulin sensitivity among glucose tolerant Caucasians
✍ Scribed by J. Ek; G. Andersen; S. A. Urhammer; L. Hansen; B. Carstensen; K. Borch-Johnsen; T. Drivsholm; L. Berglund; T. Hansen; H. Lithell; O. Pedersen
- Publisher
- Springer
- Year
- 2001
- Tongue
- English
- Weight
- 84 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0012-186X
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Background Peroxisome proliferators-activated receptor γ (PPAR γ ) is a nuclear hormone receptor that serves as a master regulator of adipocytesspecific genes contributing to adipocytes differentiation, susceptibility to obesity, and insulin sensitivity. The substitution of proline to alanine at cod
## Background: The peroxisome proliferator-activated receptor-gamma (ppargamma) gene has been recently associated with type 2 diabetes, obesity and traits depending on vegf expression (e.g. retinopathy). the ppargamma gene and its coactivator, the peroxisome proliferator-activated receptor-gamma co