𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The peptide-binding specificity of HLA-B27 subtype (B∗2705) analyzed by the use of polyalanine model peptides

✍ Scribed by Doriana Fruci; Giulia Greco; Eliana Vigneti; Nobuyuki Tanigaki; Richard H. Butler; Roberto Tosi

Book ID
119145345
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
412 KB
Volume
41
Category
Article
ISSN
0198-8859

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Differences in peptide-binding specifici
Differences in peptide-binding specificity of two ankylosing spondylitis-associated HLA-B27 subtypes
✍ Doriana Fruci; Richard H. Butler; Giulia Greco; Paolo Rovero; Lazlo Pazmany; Eli 📂 Article 📅 1995 🏛 Springer-Verlag 🌐 English ⚖ 590 KB

Two HLA-B27 subtypes, B'2702 and B'2705, both associated with ankylosing spondylitis, were tested for binding affinity with a panel of polyalanine model nonapeptides carrying Arg at position 2 (P2) and a series of different amino acids at position 9 (P9)\_ The alpha chains were isolated from BTB(B\*

Modulation of peptide binding by HLA-B27
Modulation of peptide binding by HLA-B27 polymorphism in pockets A and B, and peptide specificity of B*2703
✍ José A. Villadangos; Begoña Galocha; Fernando García; Juan P. Albar; José A. Lóp 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 988 KB

## Modulation of peptide binding by HLA-B27 polymorphism in pockets A and B, and peptide specificity of B*2703 The results in this study address three aspects of peptide binding to the diseaseassociated antigen HLA-B27 and its modulation by polymorphism: the contribution of major anchor residues 2

Binding of rationally designed non-natur
Binding of rationally designed non-natural peptides to the human leukocyte antigen HLA-B*2705
✍ Stefan Krebs; Gerd Folkers; Didier Rognan 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 274 KB

High-affinity ligands of non-peptidic nature, binding to the class I major histocompatibility complex protein HLA B\*2705 whose expression is strongly linked to the pathogenesis of the autoimmune disease ankylosing spondylitis, should give way to a selective immunotherapy by blocking or antagonising

Overlapping peptide-binding specificitie
Overlapping peptide-binding specificities of HLA–B27 and B39: Evidence for a role of peptide supermotif in the pathogenesis of spondylarthropathies
✍ Yuji Sobao; Naoyuki Tsuchiya; Masafumi Takiguchi; Katsushi Tokunaga 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 187 KB 👁 2 views

Previous studies indicated the increase of HLA-B39 among HLA-B27 negative patients with spondylarthropathies (SpA). This study was performed to examine whether the natural ligands of HLA-B27 are capable of binding to HLA-B39. Methods. Peptides were synthesized according to the sequences of known nat