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The pathogenesis and treatment of large granular lymphocyte leukemia

โœ Scribed by Steinway, Steven Nathaniel; LeBlanc, Francis; Loughran, Thomas P.


Book ID
121530724
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
685 KB
Volume
28
Category
Article
ISSN
0268-960X

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Treatment of refractory large granular l
โœ Edelman, Martin J.; O'Donnell, Robert T.; Meadows, Ivan ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 125 KB ๐Ÿ‘ 2 views

A 50-year-old man with large granular lymphocytic leukemia (CD3+, CD8+) complicated by severe pancytopenia and life-threatening infections refractory to therapy with prednisone, methotrexate, cyclosporine, and G-CSF is described. Treatment with two cycles of 2-chlorodeoxyadenosine (2-CDA) at 0.1 mg/