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The paternal chromosome 9 and the maternal chromosome 22 are preferentially rearranged in chronic myeloid leukaemia

✍ Scribed by Olicio, R; Rivero, M B; Seuánez, H N

Book ID: 110055978
Publisher: Nature Publishing Group
Year: 2004
Tongue: English
Weight: 44 KB
Volume: 18
Category: Article
ISSN: 0887-6924
DOI: 10.1038/sj.leu.2403455

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## Abstract This report describes a chronic myelogenous leukaemia patient with an apparently normal bone marrow karyotype but __BCR/ABL__ fusion‐gene‐positive. Commercial FISH probes showed an atypical pattern and the __BCR/ABL__ fusion transcript was detected by RT‐PCR, but not the reciprocal __AB