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The Partial Degradation and Reconstitution of the “A” Ring of Estradiol 1

✍ Scribed by Hartman, John A.; Tomasewski, Arthur J.; Dreiding, Andre S.


Book ID
127060778
Publisher
American Chemical Society
Year
1956
Tongue
English
Weight
689 KB
Volume
78
Category
Article
ISSN
0002-7863

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The reactions of the 4,5-bis(trifluoromethyl)-1,3,2diazasilole derivative 1 with the sterically encumbered silylenes R 2 Si, R = tBu, 2,4,6-Me 3 C 6 H 2 , proceed by partial degradation of one of the CF 3 groups to furnish the N-di-tertbutylfluorosilyl (3 a) or N-fluorodimesitylsilyl (3 b) substi-tu