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The Papillon-Lefèvre syndrome: Neutrophil dysfunction with severe periodontal disease

✍ Scribed by Thomas E. Van Dyke; Martin A. Taubman; Jeffrey L. Ebersole; Anne D. Haffajee; Sigmund S. Socransky; Daniel J. Smith; Robert J. Genco

Book ID
118117369
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
728 KB
Volume
31
Category
Article
ISSN
1090-2341

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## Communicated by Mark H. Paalman We have previously reported that loss-of-function mutations in the cathepsin C gene (CTSC) result in Papillon-Lefe `vre syndrome, an autosomal recessive condition characterized by palmoplantar keratosis and early-onset, severe periodontitis. Others have also repo