The p53 codon 72 polymorphism in black South African women and the risk of cervical cancer
β Scribed by Rosemary Pegoraro; Jack Moodley; Shunbagavelli Naiker; Pamela Lanning; Lee Rom
- Book ID
- 111159736
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 158 KB
- Volume
- 107
- Category
- Article
- ISSN
- 1470-0328
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## Abstract The p53 gene is involved in the control of cellβcycle arrest and apoptosis. The germline Arg72Pro polymorphism alters the protein's biochemical functions, and may confer individual susceptibility to skin cancer. We evaluated the association of the Arg72Pro polymorphism with skin cancer
## Abstract The polymorphisms of the tumor suppressor gene p53 have been extensively investigated in numerous malignant tumors, particularly carcinomas associated with human papillomavirus (HPV) infection. However, the results remain controversial. To address a potential correlation between the p53