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The p50-p50 NF-κB complex as a stimulus-specific repressor of gene activation

✍ Scribed by Xin Tong; Lei Yin; Raymond Washington; Daniel W. Rosenberg; Charles Giardina


Book ID
111598770
Publisher
Springer
Year
2004
Tongue
English
Weight
567 KB
Volume
265
Category
Article
ISSN
0300-8177

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## Abstract The effect of two different DNA minor groove binding molecules, Hoechst 33258 and distamycin A, on the binding kinetics of NF‐κB p50 to three different specific DNA sequences was studied at various salt concentrations. Distamycin A was shown to significantly increase the dissociation ra