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Annexin A4 interacts with the NF-κB p50 subunit and modulates NF-κB transcriptional activity in a Ca2+-dependent manner

✍ Scribed by Young-Joo Jeon; Do-Hyung Kim; Hyeyun Jung; Sang J. Chung; Seung-Wook Chi; Sayeon Cho; Sang Chul Lee; Byoung Chul Park; Sung Goo Park; Kwang-Hee Bae

Publisher: Springer
Year: 2010
Tongue: English
Weight: 659 KB
Volume: 67
Category: Article
ISSN: 1420-682X
DOI: 10.1007/s00018-010-0331-9

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## Abstract The effect of two different DNA minor groove binding molecules, Hoechst 33258 and distamycin A, on the binding kinetics of NF‐κB p50 to three different specific DNA sequences was studied at various salt concentrations. Distamycin A was shown to significantly increase the dissociation ra