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The oxime bond formation as a useful tool for the preparation of oligonucleotide conjugates

✍ Scribed by Yashveer Singh; Om Prakash Edupuganti; Mathilde Villien; Éric Defrancq; Pascal Dumy

Book ID
108109564
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
351 KB
Volume
8
Category
Article
ISSN
1631-0748

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Efficient preparation of carbohydrate–ol
Efficient preparation of carbohydrate–oligonucleotide conjugates (COCs) using oxime bond formation
✍ Damien Forget; Olivier Renaudet; Eric Defrancq; Pascal Dumy 📂 Article 📅 2001 🏛 Elsevier Science 🌐 French ⚖ 156 KB

Chemoselective ligation of carbohydrates to oligonucleotides was accomplished by oxime bond formation. The conjugation was performed by reacting an oxyamino sugar with an oligonucleotide containing an aldehyde moiety at the 5%-end. The carbohydrate-oligonucleotide conjugates (COCs) were obtained in

ChemInform Abstract: Efficient Preparati
ChemInform Abstract: Efficient Preparation of Carbohydrate—Oligonucleotide Conjugates (COCs) Using Oxime Bond Formation.
✍ Damien Forget; Olivier Renaudet; Eric Defrancq; Pascal Dumy 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 24 KB 👁 2 views

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