The oxidation induced rearrangement of carbapenems to carbacephams

✍ Scribed by Gregg B. Feigelson

• Book ID: 104259163
• Publisher: Elsevier Science
• Year: 1998
• Tongue: French
• Weight: 180 KB
• Volume: 39
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(98)00510-3

✦ Synopsis

Upon dihydroxylation, carbapenems with an exocyclic vinyl sulfone at C-2 were found to rearrange to 2-keto-3.hydroxy carbacephams. These products could then be converted into the corresponding carbacephems.