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The one-pot process for the preparation ofN-monoalkyl aromatic amines from nitroarene derivatives

✍ Scribed by JianHong Jia; WeiJian Sheng; Liang Han; YuJin Li; JianRong Gao; JunFei Tu


Book ID
107348945
Publisher
SP Science China Press
Year
2009
Tongue
English
Weight
615 KB
Volume
52
Category
Article
ISSN
1674-7291

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## Abstract Reaction of an isocyanide with an electron‐poor aromatic aldehyde in the presence of silica nanoparticles (silica NP; __ca.__ 42β€…nm) proceeds smoothly at room temperature to afford 2‐hydroxyacetamide derivatives in high yields (__Schemeβ€…1__ and __Tableβ€…1__).