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The oncogenic JUNB/CD30 axis contributes to cell cycle deregulation in ALK+ anaplastic large cell lymphoma

✍ Scribed by Atsaves, Vassilis; Lekakis, Lazaros; Drakos, Elias; Leventaki, Vasiliki; Ghaderi, Mehran; Baltatzis, George E.; Chioureas, Dimitris; Jones, Dan; Feretzaki, Marianna; Liakou, Chryssoula; Panayiotidis, Panayiotis; Gorgoulis, Vassilis; Patsouris, Efstratios; Medeiros, L. Jeffrey; Claret, Francois X.; Rassidakis, George Z.


Book ID
126064441
Publisher
John Wiley and Sons
Year
2014
Tongue
English
Weight
771 KB
Volume
167
Category
Article
ISSN
0007-1048

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CD30 and the NPM-ALK fusion protein (p80
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## Abstract The t(2;5)(p23;q35) translocation results in the formation of a unique chimeric NPM‐ALK protein (p80). Expression of this protein is considered to be one of the clinical features of anaplastic large cell lymphoma (ALCL). Recently recognized as one clinical subtype of ALCL, the small cel