The O-neophyl rearrangement of 1,1-diarylalkoxyl radicals. Experimental evidence for the formation of an intermediate 1-oxaspiro[2,5]octadienyl radical
β Scribed by Massimo Bietti; Alessandra Calcagni; Daniel Oscar Cicero; Roberto Martella; Michela Salamone
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- French
- Weight
- 329 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0040-4039
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1c 3c(9%) + + 6c(17%) 2c(42%) 5c(13%) 4c(16%) FeBr 2 THF TETRAHEDRON LETTERS Tetrahedron Letters 42 (2001) 9027-9030
An excellent substrate of methylmalonyl-CoA mutase, methylmalonyl-carba-(dethia) coenzyme A (methylmalonyl-CH(2)-CoA), was synthesized by a chemoenzymatic method and its alpha-proton was exchanged with deuterium by long-term incubation in deuterium oxide at pH 6.9. After addition of highly purified
concluded [301 that CFH, + CF,H + CFH + CF,H, did not occur. Taking LUP > 0 gives a similar result, AH;