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The nuclear membrane prevents replication of human G2 nuclei but not G1 nuclei in xenopus egg extract


Book ID
113406934
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
128 KB
Volume
2
Category
Article
ISSN
0962-8924

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Xenopus egg extracts initiate replication at specific origin sites within mammalian G1-phase nuclei. Similarly, S-phase extracts from Saccharomyces cerevisiae initiate DNA replication within yeast nuclei at specific yeast origin sequences. Here we show that Xenopus egg extracts can initiate DNA repl