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Recombinant Cdt1 Induces Rereplication of G2 Nuclei in Xenopus Egg Extracts

✍ Scribed by Domenico Maiorano; Liliana Krasinska; Malik Lutzmann; Marcel Mechali

Book ID
113559217
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
284 KB
Volume
15
Category
Article
ISSN
0960-9822

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Xenopus egg extracts initiate replication at specific origin sites within mammalian G1-phase nuclei. Similarly, S-phase extracts from Saccharomyces cerevisiae initiate DNA replication within yeast nuclei at specific yeast origin sequences. Here we show that Xenopus egg extracts can initiate DNA repl