✦ LIBER ✦

The novel tumor suppressor HPP1 restores interferon sensitivity in colorectal cancer cells via activation of STAT 1 and 2 signaling pathways

✍ Scribed by Jonathan Matthew Hernandez; Abul Elahi; David Shibata

Book ID: 113680148
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 107 KB
Volume: 211
Category: Article
ISSN: 1072-7515
DOI: 10.1016/j.jamcollsurg.2010.06.319

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## Abstract Aberrant janus kinase/signal transducers and activators of transcription (JAK/STAT) signaling is involved in the oncogenesis of several cancers. Suppressors of cytokine signaling (SOCS) genes and SH2‐containing protein tyrosine phosphatase 1 (SHP1) proteins, which are negative regulator