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PKD1 Induces p21waf1 and Regulation of the Cell Cycle via Direct Activation of the JAK-STAT Signaling Pathway in a Process Requiring PKD2

✍ Scribed by Anil Kumar Bhunia; Klaus Piontek; Alessandra Boletta; Lijuan Liu; Feng Qian; Pei-Ning Xu; F.Joseph Germino; Gregory G Germino

Book ID
117269103
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
681 KB
Volume
109
Category
Article
ISSN
0092-8674

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## Abstract Aberrant janus kinase/signal transducers and activators of transcription (JAK/STAT) signaling is involved in the oncogenesis of several cancers. Suppressors of cytokine signaling (SOCS) genes and SH2‐containing protein tyrosine phosphatase 1 (SHP1) proteins, which are negative regulator