The novel dual GC-A and GC-B designer natriuretic peptide, cenderitide (CD-NP), enhances the renal actions of furosemide in a model of severe heart failure
โ Scribed by Lisa C Costello-Boerrigter; Guido Boerrigter; Sarah Mangiafico; Alessandro Cataliotti; John C Burnett
- Publisher
- BioMed Central
- Year
- 2011
- Tongue
- English
- Weight
- 94 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1471-2210
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๐ SIMILAR VOLUMES
Costello-Boerrigter et al.: Cenderitide (CD-NP), a novel peptide designed to activate both guanylyl cyclase B and A, activates the second messenger cGMP, suppresses aldosterone, and preserves GFR without reducing blood pressure in a proof-of-concept study in patients with chronic heart failure.
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