✦ LIBER ✦
Cenderitide (CD-NP), a novel peptide designed to activate both guanylyl cyclase B and A, activates the second messenger cGMP, suppresses aldosterone, and preserves GFR without reducing blood pressure in a proof-of-concept study in patients with chronic heart failure
✍ Scribed by Lisa C Costello-Boerrigter; John A Schirger; Wayne L Miller; Guido Boerrigter; Horng H Chen; Ruth Kempf; Candace Y Lee; John C Burnett
- Publisher
- BioMed Central
- Year
- 2011
- Tongue
- English
- Weight
- 135 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1471-2210
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✦ Synopsis
Costello-Boerrigter et al.:
Cenderitide (CD-NP), a novel peptide designed to activate both guanylyl cyclase B and A, activates the second messenger cGMP, suppresses aldosterone, and preserves GFR without reducing blood pressure in a proof-of-concept study in patients with chronic heart failure.