Statistical issues on the determination
β
Takashi Yanagawa; Yasuki Kikuchi
π
Article
π
2001
π
John Wiley and Sons
π
English
β 182 KB
## Abstract The determination of a safe exposure level for toxic agents, often defined as the highest dose level with no toxic effect and termed the noβobservedβadverseβeffect level (NOAEL) is reviewed. The conventional methods based on statistical tests are criticized, particularly when the sample