The Nitroethylation of Indoles. III. 1-3 A Synthetic Route to Substituted Tryptamines
β Scribed by Noland, Wayland E.; Lange, Ronald F.
- Book ID
- 126172815
- Publisher
- American Chemical Society
- Year
- 1959
- Tongue
- English
- Weight
- 758 KB
- Volume
- 81
- Category
- Article
- ISSN
- 0002-7863
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π SIMILAR VOLUMES
## Indoles, 111') Lactamisation of 4.9-Dihydropyrano [3.4-b]indol-1( 3m-ones. -
We describe here the synthesis In two steps from the appropriately substituted t3-tetralones of 3-methyl-1,2,4,5-tetrahydro-8H-benz[e]indole, la, and of its 8,9-dimethoxy analog, lb. Insofar as we are aware, no compounds
## Abstract The reaction of 2 with 2βmethoxyethylamine in the presence of ZnCl~2~ afforded imine 3, which was reduced with NaBH~4~ to amine 4 without isolation. After deprotection of the carbonyl function by treatment with benzeneseleninic anhydride, ketone 5 was converted to compound 6 with 2βoxob