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The NHCs-mediated cross-coupling of aromatic aldehydes with benzyl halides: synthesis of α-aryl ketones

✍ Scribed by Lu Lin; Yi Li; Wenting Du; Wei-Ping Deng


Book ID
118501503
Publisher
Elsevier Science
Year
2010
Tongue
French
Weight
419 KB
Volume
51
Category
Article
ISSN
0040-4039

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Indium-mediated coupling of bromoacetonitrile and 2-bromopropionitrile with a variety of aromatic acyl cyanides afforded the corresponding aromatic a-cyano ketones in moderate to good yields under mild and neutral conditions.