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The neuroprotectant ebselen inhibits oxidative DNA damage induced by dopamine in the presence of copper ions

✍ Scribed by Yunbo Li; Zhuoxiao Cao


Book ID
117472864
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
260 KB
Volume
330
Category
Article
ISSN
0304-3940

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Electrode potential-controlled DNA damag
✍ Miroslav Fojta; LudΔ•k Havran; Tatiana KubičÑrovΓ‘; Emil Paleček πŸ“‚ Article πŸ“… 2002 πŸ› Elsevier Science 🌐 English βš– 79 KB

Supercoiled (sc) DNA immobilized at the surface of a hanging mercury drop electrode was cleaved by reactive oxygen species generated by an electrochemically modulated reaction of copper ions, hydrogen peroxide and/or oxygen. The cleavage was observed in a certain potential region where redox cycling