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The negative regulation of Toll-like receptor and associated pathways

✍ Scribed by Lang, Tali; Mansell, Ashley


Book ID
110041442
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
273 KB
Volume
85
Category
Article
ISSN
0818-9641

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Nucleic acid structures are highly conserved through evolution and when self nucleic acids are aberrantly detected by toll-like receptors (TLRs) they contribute to autoimmune disease. For this reason, multiple regulatory mechanisms exist to prevent immune responses to self nucleic acids. TLR9 is a n