## Abstract ## Background The Alzheimer's Disease Assessment Scale (ADAS) is often used in international multicenter trials. Use across countries presupposes correct translation and adaptation of the scale, and maintenance of its psychometric properties. ## Objectives To compare the various tran
The need for a consensus in the use of assessment tools for Alzheimer's disease: the Feasibility Study (assessment tools for dementia in Alzheimer Centres across Europe), a European Alzheimer's Disease Consortium's (EADC) survey
✍ Scribed by Santiago Paulino Ramirez Diaz; Pedro Gil Gregório; Jose Manuel Ribera Casado; Emma Reynish; Pierre Jean Ousset; Bruno Vellas; Eric Salmon
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 64 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0885-6230
- DOI
- 10.1002/gps.1355
No coin nor oath required. For personal study only.
✦ Synopsis
Aims
To ensure that all Alzheimer centres across Europe are capable of using a similar method of data collection. Information about the patient assessment tools used by each participating centre was obtained and normal clinical practice in each EADC centre was documented by collecting data from routine new patient consultation. Methods Twenty new consecutive patients with objective memory impairment were recruited in each Alzheimer centre over 6 months. Each patient consultation was carried out according to routine clinical practice. Patient data were recorded using the anonymous patient protocol (demographic, diagnosis, MMSE score, patient assessment scales, and most prominent behavioural problem). Information about neuropsychological assessment tools used in each centre was take to account to harmonise research practice for future multicentre collaboration. Results Seven hundred and four patients from 36 memory clinics in 13 countries across Europe participated in the study.
[M:F ratio 0.67. Mean age 75.4 SD 9.3 (51-102) Mean MMSE 21 SD 6 (0-30)] Five hundred and fifty-five patients had a clinical diagnosis of dementia [Alzheimer's disease (68.5%), vascular dementia (10.3%), frontal lobe dementia (5.6%), Lewy body dementia (4.1%), mixed dementia (5.6%)].
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