## Abstract Here we demonstrate a new basis of signal change in magnetic resonance imaging (MRI) related to neuronal function, independent of blood oxygenation or flow. Time series MRI data acquired from living, superfused brain slices of adult rats revealed that the signal intensity reversibly inc
The nature of spatiotemporal changes in cerebral hemodynamics as manifested in functional magnetic resonance imaging
✍ Scribed by Partha P. Mitra; Seiji Ogawa; Xiaoping Hu; Kǎmil Uǧurbil
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 1021 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0740-3194
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
The nature of changes in rapidly acquired magnetic resonance images of the brain was studied by using a denoising method and spectral techniques optimally suited to short time series. It was found that the stimulus related changes have a complex spatiotemporal structure even for simple visual stimuli. Apart from a low frequency window, the non‐stimulusrelated changes were found to correspond in detail to either breathing or heartbeat, although these two sources show different patterns of spatial coherence in the image. At low frequencies, oscillations with frequencies around 0.1 Hz were observed, also with nontrivial space‐time structure, which are likely to be vasomotor in origin.
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