Potential effects of the coadministration of single doses of aspirin (325mg) and of benazepril hydrochloride (20 mg) on the pharmacokinetics and the metabolism of these two drugs were evaluated in 12 healthy subjects. Plasma concentration profiles of benazepril, its active metabolite benazeprilat, a
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The nature of interaction between the carboxylate of substrates and the guanidinium moiety of Arg-145 in carboxypeptidase A probed by inhibitors of the enzyme
โ Scribed by Dong H. Kim; Jeong- il Park
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 231 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0960-894X
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## Abstract To prevent the precipitation reaction between glycyrrhizin (**1**) and berberine (**3**) in the decoctions of __Glycyrrhiza__/__Coptis__ rhizome or __Glycyrrhiza__/__Phellodendron__ bark, the presence of cyclodextrin (CD) in the mixture was proven to be effective. The preventing effect