𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The nature of conditionally lethal temperature-sensitive mutations in somatic cells

✍ Scribed by Louis Siminovitch; Larry H. Thompson

Book ID
102882065
Publisher
John Wiley and Sons
Year
1978
Tongue
English
Weight
639 KB
Volume
95
Category
Article
ISSN
0021-9541

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## Abstract Hybrid clones were obtained between a mouse cell line (3TP) and a temperature‐sensitive Chinese hamster cell line (K12) unable to grow at 40Β° because of a __ts__ defect apparently located at the G1/S transition. The great majority of hybrid clones grew at 40Β°, showing the __ts__ defect